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whole exome variant filtering

Hello, I need to do whole exome variant analysis from ready vcf.gz files. Only option I know is filtering through Illumina Variant Interpreter

Are there better options for whole exome variant filtering than Variant Interpreter?

Thank you!

next-gen

Well, in which way do you want to filter? - low read depth?; strand bias?; functionality / pathogenicity [of the variants]?

For ease of use, Ensembl's Variant Effect Predictor may be what you need.

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