The code I am running is posted below. Here "ec_results" is a file of type 'character'. Also, "ec_results" is the direct output of the toptable function.

library('dorothea')
library(bcellViper)

data(bcellViper, package = "bcellViper")
data(dorothea_hs, package = "dorothea")

tf_activities <- run_viper(ec_results, dorothea_hs)

The error I am getting is this:

Computing the association scores

Computing regulons enrichment with aREA

 Error in wts^2: non-numeric argument to binary operator
 Traceback:

 1. run_viper(ec_results, dorothea_hs)
 2. run_viper.data.frame(ec_results, dorothea_hs)
 3. run_viper(as.matrix(input), regulons = regulons, options = options, 
 .     tidy = tidy)
 4. run_viper.matrix(as.matrix(input), regulons = regulons, options = options, 
  .     tidy = tidy)
 5. do.call(viper::viper, c(list(eset = input, regulon = .df2regulon(regulons)), 
  .     options))
 6. (function (eset, regulon, dnull = NULL, pleiotropy = FALSE, nes = TRUE, 
  .     method = c("none", "scale", "rank", "mad", "ttest"), bootstraps = 0, 
  .     minsize = 25, adaptive.size = FALSE, eset.filter = TRUE, 
  .     mvws = 1, pleiotropyArgs = list(regulators = 0.05, shadow = 0.05, 
  .         targets = 10, penalty = 20, method = "adaptive"), cores = 1, 
  .     verbose = TRUE)

The error continues for multiple lines ~50 lines more.

Any help is appreciated! Thanks!