structure conversion of protein

Question

[siwangi.srivastava25]

which is the bioinformatic tool that can be used for the conversion of monomer of protein to dimer or trimer?

Answer 1

[Mensur Dlakic]

Generally speaking, there is no such a thing. If you have a homologous structure to your protein that is in different multimerization state than yours, you may be able to use them to predict how your protein will multimerize, but it will be only a prediction. Lastly, some proteins are known to exist as multimers but only a monomer is present in PDB files. In such cases there are symmetry operators in PDB files that specify how subunits should be rotated and translated to create a multimer.

Answer 2

[jgreener]

PDB files have associated biological assembly files with likely multimeric states present. Click the "Download Files" link on a PDB entry to find them. They are created automatically from symmetry operations listed in the PDB file header.