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Calculate Ka/Ks using examples of two sequences.

Here is two sequences seq1: ATG AAT AGA GAA GGC seq2: ATC TAT AGA GTA CCC seq1 is reference sequence. Now how to calculate the Ka and Ks? could anyone help? much appreicated.

genome

Do you want to calculate Ka/Ks ratio by hand or just use a tool? There are at least six different methods to calculate Ka/Ks ratio.

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