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Append/Merge/Combining multiple VCF files

Hello Everyone,

I have a list of VCF files from specific ethnicity such as American Indian, Chinese, European etc

Under each ethnicity, I have around 100+ files.

Currently, I computed the VARIANT QC metrics such as call_rate, n_het etc like below for one file

image is here

How can I do this across all files under a specific ethnicity?

Can help me with this?

Is there any python or R or Unix approach to do this?

sequence rna-seq next-gen sequencing chip-seq

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