I agree. I would edit your CV to emphasise your bioinformatics skills and then start to apply for jobs. You would have to apply to 'Analyst'-type jobs, which are effectively entry-level in Bioinformatics. Ironically, from what I can gauge, some companies will be happier to bring in an MSc-level bioinformatician as opposed to a PhD-level bioinformatician, depending on the role, of course.
You will need a cover letter, too, to justify why you want to go back into Bioinformatics. You don't have to explain why you left, originally - just say 'personal matter'.
Also, job availability differs depending on your location, of course, and whether or not you can move.