Hello everyone, I have raw data from Whole Exome Sequencing (WES) and would like to perform a reanalysis. I am looking for guidance on where …

Hello everyone, I am looking for a method to perform a single-cell compositional analysis comparing two conditions (with 9 replicates per phenotype). However, I am …

Hello, Let say I've three independent cohorts on which I want to perform GWAS on a specific continous phenotype. This phenotype is not normally distributed …

I am attempting to conduct a meta analysis of GEO datasets using crossmeta (https://bioconductor.org/packages/release/bioc/html/crossmeta.html). The tutorial gives a function for downloading the datasets: "get_raw", but …

I am attempting to conduct a meta-analysis in R of differentially-expressed genes across a variety of pain conditions. After searching the literature for whole genome …

Hello, I am looking to determined whether SNP associated with a disease phenotype are enriched within a particular regulatory region. I am looking to compare …

Hi all, I have gene expressions data sets from three species (human, rat and mouse). Each data set either has two groups of individuals (i.e. …

As the meta-analysis suite consists of three packages 1) MetaQC : For quality control 2) MetaPCA: For dimensional reduction 3) MetaDE: To identify deferentially expressed …

Hi everyone, We have exome-chip data (disease cases and healthy controls) from three different studies. Currently, for each study I have performed group-based tests (CMC …

<p>I have an association study analysis (GWAS) that does not reach genome-wide significance (max p-value &lt;10E-5), and there is a potential additional sample (so with …