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Unequal group size

Can you compare 5 males in one group versus 10 females in another group by either a t-test or a wilcoxin test ?

I heard that the group size difference would be a problem. If you can't then is there a way to test them in a way that accounts for the difference in sample group size.

Thank you in advance

statistics

Can you summarize what the data looks like, and what question you want to answer with the data?

Hypothetically speaking could be height, weight, white blood cell counts etc. If the group size was 10 females versus 5 males would that invalidate a t-test or a wilcoxin test for example ? How would you address the difference in group size assuming it was a problem?

Thanks for your help in advance

Thanks h.mon for the links.

It looks like a Welch's t-test or a Mann.Whitney (assuming the sample size is not too small) is the way to go here.

Thanks again

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