I'm seeking collaboration to create a comprehensive Excel table detailing the LOEUF (Loss-of-Function Observed/Expected Upper Bound Fraction) for each gene, a crucial metric for understanding …

Hi All, Anyone can share me the formula how DEseq calculate P-value? Thanks Fraz

Hi All, Who can share a command to download `Height` information from `UKB` with `ukbfetch`. Thanks.

Hi All, Who can share a script to calculate RVIS (Residual Variation Intolerance Score). Petrovski S., Wang Q., Heinzen E.L., Allen A.S., Goldstein D.B. (2013). …

Hi All, Who can share an annotation file for the latest version of ancestral alleles for dbSNP152 or dbSNP153 Thanks.

Hi All, Who can share a script to download human gene fasta/sequences for FGF1, FGF2, FGF3, FGF4, FGF5, FGF6 and FGF7 at the same time? …

Hi All, Who can help me to explain how to calculate "expected loss-of-function variants" for a gene? any formula? a gene with a LoF oe …

Hi All, Who can share a script to transfer mutation VCF files to 3-base mutation pattern: Bekow is the output i want to obtain. I …

Hi All, I want to download the annotation of 'loss-of-function' annotation in [gnomAD][1] and [Bravo][2] database. However, it seem you can find these annotation when …

Hi All, Is there any perl expert who has completed the perl script for LD (genetic) inferring? Can you share the script, Thanks. Best regards,