Hi All,

Who can share a script to calculate RVIS (Residual Variation Intolerance Score).

Petrovski S., Wang Q., Heinzen E.L., Allen A.S., Goldstein D.B. (2013). Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes. PLOS Genetics, doi: 10.1371/journal.pgen.1003709

Thanks.