Which Functional Annotations Could Be Useful?
Analyzing a genome, for a generic gene, which functional annotations (e.g from Gene Ontology) can help understanding its meaning/function or, at least, provide helpful informations?
- Annotations of that gene
- Annotations of orthologous genes (?)
- Annotations of paralogous genes (?)
- Co-expressed genes (given a biological condition) (?)
- What else?
Thank you.
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It is unclear what you are trying to accomplish. What is a generic gene?
Ok, sorry. With "generic" I mean not "whatever", not particular a case. Is it clear now? Thank you.
The answers to your question will depend heavily on what you are trying to accomplish and what biological system you are working in. Clinical cancer samples? Model organism? Microbiome? Whole-genome view? Comparative genomics? I think that is what Zev meant by "what are you trying to accomplish?"
In the case of Whole-genome view?
PLEASE, help us out here. If you are not a biologist, please ask your biology collaborator to help you clarify your question with biological context, what data you are working with, and what biological questions you are trying to answer.