best package for DEG analysis from scRNA-seq data

I have log2 transformed tpm data of a single-cell RNA-seq experiment. What is the best R package to find differentially expressed genes from such data? from what I know DEseq is not optimal for scRNAseq.

Thanks,

rna-seq

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updated 6.2 years ago by igor

• written 6.2 years ago by jabbari.parnian •

1 answer

Seurat is a popular scRNA-seq analysis package. You should check the differential expression vignette they have where they describe a few different methods: https://satijalab.org/seurat/v3.1/de_vignette.html

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written 6.2 years ago by igor

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