This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Amino acid substitution to nucleotide substitution conversion

I have a list of oncogenic mutations from the OncoKB database. The data looks someting like this

Gene    Alteration    Oncogenicity
CBL      P417A        likely oncogenic
CBL      N454D        likely neutral

I want to convert the above data set into the following format

Gene    Alteration   Location  Pathogenicity
CBL      P417A       chrX:Y-Z   likely oncogenic
CBL      N454D       chrA:B-C   likely neutral

Where X,A are chromosome numbers and B,C,Y,Z are genomic positions. Is there a straightforward way to do this? I have 1000s of such mutations.

r sequencing

0 answers

No answers yet.

Log in to answer this question.