This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Metabolite profiling from microbial community

Hi community!!! I want to get the metabolite profile for microbial community. I have 16S rRNA sequence data from which I have gone to genus level resolution (species level cannot be reached). Can you please tell me what are the next steps and what are the softwares should I follow to get the metabolomic profile?

Are the genus level data really useful for predicting the metabolite composition?

Thanks and Regards, DC7

multi'omic metabolomic metagenomic 16s rrna
• 98 views • link
written by dpc dpc

How can one get metabolic profiling information from sequence data?

• 0 views • link
written by GenoMax GenoMax

Is it possible if I do metagenomic profiling (using Picrust) from the 16S rRNA data?

• 0 views • link
written by dpc dpc

Think about it that way: You want metabolites (so products of the metabolism) but you have DNA sequences from 16S rRNA. How could you ever make a connection? These are two completely different areas and require different experimental approaches. Answer is no, 16S does not allow inference of metabolic states.

• 0 views • link
written by ATpoint ATpoint

Okay. I understand. Thanks for the information.

• 0 views • link
written by dpc dpc

I assume you have looked at PICRUSt paper/website already?

PICRUSt is designed to estimate the gene families contributed to a metagenome by bacteria or archaea identified using 16S rRNA sequencing. I

• 0 views • link
written by GenoMax GenoMax

0 answers

No answers yet.

Log in to answer this question.

More posts like this