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Aspera ascp command line utility inside prefetch call to facilitate SRA data downloading

Hi,

I've executed the prefetch command of SRA toolkit which is in my case supposed to call the Aspera ascp command line utility internally. My command line was:

/home/sratoolkit.2.10.0-ubuntu64/bin/prefetch -a "/home/.aspera/connect/bin/ascp|/home/.aspera/connect/etc/asperaweb_id_dsa.openssh" -O /home/Data -X 100000000 SRR6856355

However, in the log file i got :

2020-03-18T11:15:00 prefetch.2.10.0: 1) Downloading 'SRR6856357'...
2020-03-18T11:15:00 prefetch.2.10.0: Downloading via https...
2020-03-18T12:51:32 prefetch.2.10.0: https download succeed

It's seems that, prefetch does not use the Aspera ascp.

How can i turn on Aspera ascp to speed up the process?

genome next-gen

1 answer

SRA data can no longer be downloaded via Aspera, see https://github.com/ncbi/sra-tools/issues/255

Thank you for sharing this information. Bad news.It's too slow via https. Any suggestion to accelerate the download?

No, just wait and have coffee :) Still, the file SRR6856357 is not overly large, should actually not take a long time. I could download it with prefetch in little less than two minutes. Maybe you have a slow internet connection or massive I/O bottlenecks.

Search for the file with https://sra-explorer.info/ and then try the download links it provides. Maybe some work better.

Hi! That's interesting, as for me it takes almost 1 hour to download SRR6856357 with prefetch on HPC cluster.

Probably a bad connection then or massive I/O trouble, we had then when multiple file servers were malfunctioning long ago. I suggest you contact the admin for this.

Thanks a lot. Will try to manage that.

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