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Conversion of human miRBase Accession/Name/Sequence to murine

Hi Everyone,

I was hoping you could help. I have a list of differentially expressed miRs clusters in mouse. I want to apply this expression date to lists of differentially expressed human miR datasets. I prefer to use an R workflow.

To do this ideally I think I would need to join the names/IDs/sequences of the human data to the mouse. At the moment, this only partially works. e.g. miR-21 human would not match to miR-21a in mouse.

Is there a way you would recommend doing this? Or is the conservation too poor to recommend this approach at all?

Thank you for your help!

mirbase microrna

Thanks very much for this - I've had a go with @Alastair using Biomart on the ENSEMBL Website. Using this I generated about 250 murine microRNAs from the 2000 or so human miRs.

I was wondering if there was another approach anyone can recommend? Very grateful for your help!

K

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