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Decontaminate RNASeq data from other cell types?

Hello all,

Very ambitious question coming!

So I have RNA-Seq data from CD4+ cells, which are selected using a kit. However I used CIBERSORT on them and I see that there is a significant contamination with other immune cell types, mainly B and NK cells. I was wondering if there is any way to extract only the cells of my interest?

Thanks and apologies in advance! :)

gene-expression decontamination rna-seq

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