This is a test version of Biostars. For the public version, visit https://www.biostars.org.
How is the Bolt LMM INFO Score calculated?

Hi

I am trying to find what exactly does the INFO score from the results of Bolt LMM measure (there is nothing in the user manual and google has come up empty). I am assuming that it refers to the imputation accuracy taken from the genotype probabilities but does anyone have a link or know what is the theory/formula that it is derived from?

Thanks heaps

bolt lmm
• 1,555 views • link
updated by Pierre Lindenbaum Pierre Lindenbaum • written by discombobulated • discombobulated

If you have programming experience you could look at the code otherwise consider emailing the program author directly.

• 0 views • link
written by GenoMax GenoMax

1 answer

Thanks genomax. I did as you suggested and contacted the developer. It is calculated using the formula developed by [Marchini and Howie] in their 2010 Nature Review Genetics paper.

• 0 views • link
written by discombobulated • discombobulated

Log in to answer this question.

More posts like this