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Tool to extract COG information/description

I have list of different COG numbers, and would like to retrieve a list of the COG numbers, with their corresponding function. Is there a tool for this?¨

The COG numbers look like this (always 4 digits): COG:COG1132

cog

1 answer

This tab-delimited file has what you want.

Here is general hyperlink pattern for COGs:

http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0001

By inserting your COG number instead of COG0001 you will get more detailed info.

Hi Mensur! That's exactly what I was looking for. I suppose a small script could easily fetch the right COGs from it. The A-Z letters are a very general categorization, right?

The letters are functional categories of COGs. Their meaning is described here.

I just realized, that some COGs have multiple letters. Is that because the gene harbors both categories or because it doesn't know where to put it?

It is because many proteins are multi-functional.

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