Calculating neutrality statistics like Tajima D with structural variants · Biostar

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Calculating neutrality statistics like Tajima D with structural variants

I have a set of structural variant calls for a few hundred human genomes, and I'm looking to evaluate selective pressure on each chromosome. I came across the Tajima D statistic, but most of the examples of its use are on SNP data, so I have wondered if it makes sense to use Tajima D with structural variant data. If not, can someone please recommend a sensible method for structural variants?

dna-seq population genetics structural variants

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written 7.4 years ago by lucas.lochovsky •

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