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Can we use mouse reference genome to perform DGE analysis of Zebrafish rna-seq samples?

Hi all, I have a weird question! I have some rna-seq samples from Zebrafish. Is that possible if I use mouse or human reference genome (instead of Zebrafish) to perform differential gene expression analysis on these samples?

I know we have Zebrafish reference genome. I just want to use human or mouse as these two are more well studied for down stream analysis.

Thanks,

rna-seq sequencing reference genome

Just no. Seriously, simply don't do that.

Thanks. Seriously and simply thanks!

...is this a test to see our reaction? - I find it curious that the notion even existed to do this. Was there logic behind it?

haha! not really! It was really my question!

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