Oxford Nanopore insertion vs deletion rates
Indels are a big problem in Oxford Nanopore reads due to difficulty in basecalling homopolymers. Are insertions and deletions equally likely? If the one type is more likely than the other, why don't they compensate for it in the basecaller by systematically under- or over-calling homopolymer length?
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WouterDeCoster
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BioinformaticsLad
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Short insertions and short deletions are about equally likely.
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Based on my (limited) experience with Nanopore data, looks like there was no bias towards either insertions or deletions. I don't have hard data to support this, though.