I'm considering conducting a GWAS analysis using the UK Biobank data, which involves a very large cohort of 500,000 participants. In our lab, we've previously …

Hello, I am running BOLT-LMM 2.3.5 with following conditions bolt \ --bed= bed \ --bim= bim \ --fam=fam \ --bgenFile=chr{1:22}.bgen \ --sampleFile=chr1.sample \ --bgenMinINFO=0.3 \ …

As a validation experiment, I have run the same GWAS of a quantitative phenotype derived from the UKBiobank, alongside the genomic data from the UKBiobank, …

Hello, Does anyone know/have any code to perform GWAS using BOLT-LMM for many phenotypes iteratively in bash so it is more automated, rather than running …

I'm trying run [BOLT-LMM][1] against a simulated dataset, which were generated with [plink --simulate][2], however no success: ./BOLT-LMM_v2.3.4/bolt --bfile=ds1_1gt10k --phenoUseFam --statsFile ds1_1gt10k.bolt --LDscoresUseChip --lmm ... …

Dear all, I am aiming at evaluating the genetic correlation among ~150 continuous traits measured in ~1100 twin pairs (~2200 individuals). I have already run …

Hi I am trying to find what exactly does the INFO score from the results of [Bolt LMM][1] measure (there is nothing in the user …

Hi everyone, BOLT-LMM software has help information on the use of v3 imputation BGEN format genotype data. 9.1 UK Biobank v3 imputation release The BGEN …

Hi everyone, I failed to read BGEN format imputed SNPs data ( ukb_imp_chr**_v3.bgen ) into BOLT-LMM software using csh. According to the instruction, we can …

I have GWAS SNP data for an admixed population and I would like to estimate the heritability of my trait under study. I am using …