What is CINWntUp and CINnormL?
What is CINWntUp and CINnormL?
I read a paper that uses this two things as classes but Im not sure what they represent. I imply that CIN is referring to Chromosomal instability but I don't know what WntUp & normL refer to. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214593/)
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Biostar
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louis-gil •
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louis-gil •
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Yes, CIN is chromosomal instability.
CINWntUp, in this context, relates to CIN in colon cancer samples in which the Wnt pathway is up-regulated. CINnormL relates to CIN in colon cancer samples that have a 'normal-like' expression profile.
Further details:
- https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39582
- https://www.ncbi.nlm.nih.gov/pubmed/23700391
Kevin
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Don't you think it would be useful to link us to that paper?
Thanks, I forgot to add the link.
Hello louis-gil!
It appears that your post has been cross-posted to another site: https://biology.stackexchange.com/questions/78814/question-what-is-cinwntup-and-cinnorml
This is typically not recommended as it runs the risk of annoying people in both communities.