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5.5 years ago
Jane
•
0
I've been calculating the depth of coverage this way:
number of reads * average read lenght / lenght of the reference genome
Wikipedia shows the same method. I have also been using Tablet to check my assemblies, and it seems to calculate the depth in the same way.
However, VirusDetect calculates the depth differently. The html report which VirusDetect generates shows that an assembly of three reads has a depth of over 1000, which makes no sense. And then there is the normalized depth, which I don't understand either.
How does VirusDetect calculate depth and normalized depth?
You could contact the developer directly about this.