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Remove Sequences from existing Bowtie2 index

Hello All,

I've created a bowtie2 large index, Which is a huge data set (~100GB) it took approx 2days to generate a bowtie2 index. Now I came across problems with some sequences and I want to remove it from my existing index.

Is there a way to remove sequences based on their identifiers directly from the index so that I can save indexing time.

Any help would be appreciated!!

Thank you in advance !!

bowtie2 index ngs genome

Highly likely there is no way and the only way to solve this would be to repeat the indexing.

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