What is a good hit in a blast mean ?? Which parameters should be taken in to account for calculatibg a good hit?? What if i get 78 hits while doibg a blastn or p search with evalue ranging from 0 to 98e-16 is it a good hit?? When i do a blastn or p search how will i know query sequence matches with the database...to be more specific with the help of what parameters and tools i confirm out that particular protein or nucleotide from the query sequence is present in the database... Please help..it might sound basic but the help will be really appreciated..