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What is the significance of this file in COSMIC database?
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18 months ago

I was going through the COSMIC database and came across a particular file in the downloads page. This file was named Fasta file (genes) and its description was "CDS sequence for all the genes in COSMIC". Now I understand that these are the fasta sequences of all the genes listed in the COSMIC database. But my question is are these gene sequences extracted from cancer patients? Or are they reference sequences of the genes?

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15 months ago
Titus • 850

They are references of genes they used to call mutations. The were no interests to show references cancer patients , because that will mean a de novo assembly from exom/panel sequencing . . .

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