I am considering preserving the DNA of a family member who passed away. The funeral home offers a service called DNA Memories from a Canadian company (CG Labs). They have two options: Store the DNA in their secure temperature-controlled facility, or "home DNA banking", where they somehow preserve the DNA such that it can be stored without damage "indefinitely", at room temperature. This is how they describe the technology:
"The DNA is bound to a substrate and sealed under nitrogen gas with out patent pending process. This process allows the DNA to remain in a state of suspended animation and if the vial remains sealed the DNA has an indefinite shelf life. The DNA Memorial Home Banking may be banked in non extreme conditions and room temperature for future testing at home."
My question is basically this: Is there any scientific merit to their claims (i.e. is there anything peer-reviewed on the subject of room-temperature DNA preservation for many years, using technology such as the one they describe)? Can DNA preserved in such a way really be tested later in regular DNA testing labs (or will I need a specialized lab that knows how to deal with this unique process)? Is there any possibility of a full sequencing later of DNA stored in such a fashion?
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Hello EugeneO!
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If there is another forum where I can get an answer to my question, I would really appreciate a pointer. I already tried the Biology StackExchange but it seems to be low-traffic.
Yeah, but we are the bioinformaticians. Those people staring at a terminal who are not allowed to touch samples :) SeqAnswers would also be a good option, since what you want to do will likely involve sequencing (?).
Anyway:
If you, later on, want to get any reliable results out of this I would suggest getting a second opinion of a professional genetic lab. Substrate bound DNA storage exists, such as a FTA card. It does work, but you want to make sure that it is still compatible with any tests you want to perform later on. Their proprietary solution might be great for indefinite shelf life, but if it interferes with downstream steps then it's useless.
DNA can also be stored for a very long time (years if high quality extraction) in the fridge when kept in solution (TE or just plain water).