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pacbio-illumina hybrid assemblies

We are looking into assembly with pacbio and illumina data, and wondering if there are any tools or well-validated workflows for hybrid assemblies, as well as any recommendations for coverage. this is for a eukaryotic genome. additionally, has anyone ever tried a pacbio-10XGenomics hybrid assembly?

assembly illumina pacbio hybrid assembly

1 answer

This guy seems to be trying it with quickmerge.

https://github.com/mahulchak/quickmerge/issues/22

It would be good to use the advantage of the 10x supernova assemblies and not just feed them as simple illumina data to another assembler...

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