Hi Nesrine, I recommend you to try this resource: https://www.onco.io/ You can find there upto-date mannualy curated mIR targets involved in cancer. ONCO.IO contains more then 5500 highly validated targets . ONCO.IO also contains other interactions TF-->miR, TF-->gene target and PPIs. Regards, Stas

I don't know about databases specifically for validated targets in a cancer setting; however, there are databases that store both in silico and validated target predictions, though I am not sure on the tissues used in these databases.

For in silico predictions, miRNAtap is a program that I have used to good effect; however, you may find its implementation difficult.

• A: miRNA target genes prediction.
• A: Identifying miRNA, RNA-binding sites in UTRs (also note the other answer that mentions miRBase)

If you want to make your life easier and just look up interactions (validated or predicted) in a GUI, then use miRWalk 2.0.

Kevin