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Biobase not running in R 3.5.0

Hi, everyone

I am trying to load Biobase onto my R (I'm using R studio v. 1.0.143), but it gives me the following error message:

> library("Biobase", lib.loc="/Library/Frameworks/R.framework/Versions/3.5/Resources/library")

Error: package or namespace load failed for 'Biobase': package 'Biobase' was installed by an R version with different internals; it needs to be reinstalled for use with this R version

It happened right after I updated R, from 3.3.x to 3.5.0. I did update and reinstalled the Biobase package as well just in case I have missed any previous ones. Is there anybody facing the same problem? Or even better, is there any fix for that? Or run the older version as before?

Thanks in advance!

r biobase
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written by dodausp dodausp

That was very helpful! .libPaths()was pointing to the correct directory and subfolders. What I did however was to delete the Biobase folder from my package directory and replace it by the newly downloaded one. The version was the same, but somehow it worked this way.

Thanks a lot!!!

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written by dodausp dodausp

For future reference:

Please use ADD COMMENT/ADD REPLY when responding to existing posts to keep threads logically organized. This comment belongs under @h.mon's answer.

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written by GenoMax GenoMax

1 answer

Check .libPaths(), probably the older Biobase is still installed and has precedence over the newer one. The BioConductor install page has a section on "Troubleshoot Package Installations", follow its instructions.

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written by h.mon h.mon

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