This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Error in loading SummarizedExperiment

Hi all

Before using DESeq2, I have to install SummarizedExperiment package before.

But I load it, I get the below error message.

This is my first time to use R in Mac. I tried many ways to solve this problem, but they don't work, including re-downloading DESeq2 and restarting my computer and downloading gfortran and XQuartz.

Error: package or namespace load failed for ‘SummarizedExperiment’ in dyn.load(file, DLLpath = DLLpath, ...):
unable to load shared object '/Library/Frameworks/R.framework/Versions/4.3-x86_64/Resources/library/DelayedArray/libs/DelayedArray.so':
dlopen(/Library/Frameworks/R.framework/Versions/4.3-x86_64/Resources/library/DelayedArray/libs/DelayedArray.so, 0x0006): Library not loaded: '/Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libR.dylib'
Referenced from: '/Library/Frameworks/R.framework/Versions/4.3-x86_64/Resources/library/DelayedArray/libs/DelayedArray.so'

Reason: tried: '/Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libR.dylib' (no such file), '/usr/local/lib/libR.dylib' (no such file), '/usr/lib/libR.dylib' (no such file)

Any thoughts?

deseq2 mac r summarizedexperiment
• 3,711 views • link
written by charleslv128 • charleslv128

Is this via RStudio? Does the same happen if you do it via the R console? So open a terminal, type R and then enter this? It seems it is looking for this library in the wrong place (in the 4.2 R folder rather than 4.3). What is the output of .libPaths()? The hard solution is probably to remove /Library/Frameworks/R.framework/ entirely and then install R freshly from scratch. When you say first time does that mean that R 4.2 has never been installed on this Mac before?

• 0 views • link
written by ATpoint ATpoint

Thank you for helping. Yes it's via RStudio and it happens when I use R console. I had tried to remove the entire R framework and reinstall R and RStudio, but nothing changed. The first time means R 4.2 was never used on this Mac.

> .libPaths()
[1] "/Library/Frameworks/R.framework/Versions/4.3-x86_64/Resources/library"

enter image description here enter image description here enter image description here enter image description here

• 0 views • link
written by charleslv128 • charleslv128

1 answer

https://ask.csdn.net/questions/7936084?spm=1001.2014.3001.5501

problem solved, go to see that👆

• 0 views • link
written by charleslv128 • charleslv128

Log in to answer this question.

More posts like this