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Reasons for switching from Affymetrix HGU133Plus 2.0 array platform to HGU133Plus+PM

Hi all,

For my intership research I have to work with data from the Affymetrix platforms hgu133plus 2.0 and hgu133Plus+PM. As a general question I would like to know why would one switch from platforms. As far as I know there is lots of data available for the hgu133plus 2.0 platform. So what are the advantages of using hgu133Plus+PM platfrom over the Plus2.0 . Why not stick with hgu133plus 2.0 .

So this is also more a qustions towards my supervisor, but first I would like to know the opinions and experiences from other researches on this subject.

And please let me know if there are papers I should look in to in order to learn more about this subject.

Thanks in advance!

micro-array genome affymetrix

Isn't the question "why stick to microarrays rather than going for RNA-seq?".

I think that thats a different topic by it self.

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