k means for differential gene cluster

Question

[limin201709]

Hi, I am analysising the data after RNA seq, and want to plot the clusters of gene expression generated by the k-means algorithm. And the column of the data is time series. How should I do? my thought is first performing the k means algorithm and follow by the label by k means to plot the image one by one. but which package or what kind of methods should I use?

[Kevin Blighe]

There are various tutorials out there that shows you how to do k-means clustering:

• Cluster Analysis
• Partitioning cluster analysis: Quick start guide - Unsupervised Machine Learning

And the column of the data is time series. What do you mean? - you want to perform k-means separately on the different time-points?