Generating phenotype data
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6.2 years ago
bha ▴ 80

Same question is asked at stackoverflow, but other members asking to put it at this forum. sorry for repetition.

I want to generate some phenotype data, example trait could be human height. The expression i want to use should be as:

P corresponds to phenotype

P ~ N (∑XiBi, δp)

i couldn't directly pasted above equation here,

(∑) varies from i=1 to L, is number of loci contribute to trait, could be 40

(Bi) is beta effect size

 heritability should be 40%

(δp) standard deviation for phenotype

Do apology if i make this complicated. Can i generate this phenotype in R? if so, then what's procedure should be?

SNP R • 1.0k views
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What is your intended use for this? - why do you want to do it in R? There is minimal context provided in yuor question.

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Apologies for late reply. Actually i wanted to simulate the phenotype, but now i found some programmes which can do that, for instances, gcta, dissect etc. Many thanks for your message1

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