Question of " mutation correlation"
Hello! Bioinformatic talents! I now have a basic question about genetic mutation. Can this variable be correlated with other data, like expression data? From my understanding, if the mutation data is quantifiable, then I can correlate with other omics data. Can you kindly give a comprehensive explanation please?
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It would be better to build a logistic regression model with the no mutation, heterozygote mutation, and homozygote mutation as the y variable categories, and gene expression as the predictor variable (x). For example:
glm(Mutation ~ Gene1)
You could alternatively build a linear regression model with gene expression as the y variable and the mutation categories as the predictors. For example:
lm(Gene1 ~ Mutation)
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Qingyang Xiao why did you delete this post?