chipseq identified sequences
HI All,
I am not familiar with chip-seq data analysis. I would like to know why the chip-seq identified DNA sequences for one specific protein binding site has different lengths? for example the chipseq binding regions for protein A could be between 100-2000 bps? How the binding sites ranges determined from chip-seq data?
Thanks, Morteza
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ChIP-seq data is mostly used for finding DNA binding motifs. The transcription factor binding motifs are generally short 8-12bp DNA sequences. Once motif has been identified the sequence is used as a quay for databases like JASPER, TRANSFAC® to find known transcription factor binding events.
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