What is my total number of genes in a hypergeometic distribution test?
I'm working out the significance of an overlap of two RNAseqs experiments upon knockdown of two different transcription factors. I have read previous posts on phyper in R etc and they suggest total number of genes (I assume this is all genes). I have ChIP-seq data so I know what genes are bound by my transcription factors so is my total population ALL genes or just genes bound by either transcription factor?
Thanks in advance!
C
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connor.j.rogerson •
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connor.j.rogerson •
2 answers
To find the significance of the overlap, you should use the total population of all genes.
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Hussain Ather
Have you tried BETA cistrome
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