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Can we estimate actual copy number using Segment_means in TCGA level 3 CNV data?

Hi, all!

Can we estimate actual copy number using Segment_means in TCGA level 3 CNV data?

If not, how to determine whether a gene is amplified or not?

What is the typical threshold for the determination of "Gain/Loss" for TCGA data?

Thank you!

tcga cnv copy number

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