protein-protein orientation in fusion
Hi, I am interesting in fusion of three or more antigens in a such a manner that their epitopes remain exposed. Is there any tool which may help to predict that what should be the orientation of these proteins. Your help will be greatly appreciated.
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There were several such papers:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635942/pdf/khvi-11-09-1061159.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615220/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726540/
There are a lot of protein fusion posts in Biostars:
Where To Find A Database About Fusion Protein Ant Its Interaction Partner?
Protein Protein Or Protein Dna/Rna Interaction Prediction
Determine identify of protein domains in a fusion protein
Fusion with strand orientation
See the right panel of the page for the others.