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Differential expression analysis tool for single cell RNA-seq data

I am looking for the best available differential expression analysis tool for single cell RNA-seq data.

From the literatures that did some comparisons, I found that MAST, ROTS, SCDE, DEGseq, D3E, and SAMseq seem to have good performance. Which one would you recommend based on your actual experience (most accurate, reliable, and stable tool)?

I’d greatly appreciate your advice.

Thank you very much!

single-cell rna-seq de analysis rna-seq
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updated by ashotmarg2004 • ashotmarg2004 • written by tunl tunl

3 answers

Hey man, check this, its very fresh! >> https://hemberg-lab.github.io/scRNA.seq.course/index.html

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written by lessismore lessismore

This is great! Thank you so much! Monocle vs. MAST, which one do you think is better? Thanks a lot!

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written by tunl tunl

You can also search the RNA-seq blog:

http://www.rna-seqblog.com/powsimr-power-analysis-for-bulk-and-single-cell-rna-seq-experiments/?utm_source=RNA-Seq+Blog+Subscribers

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updated by Gjain Gjain • written by theobroma22 theobroma22

Thanks so much for the information!

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written by tunl tunl

I am also new to this field but here are some useful link I've found that might be useful for whoever ends up in here:

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written by ashotmarg2004 • ashotmarg2004

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