Reading splice daa
New to this field. I have a dataset where the mutation type is splice and the alteration is coded "c.673-3T>G". How to interpret this? How do i translate this into what protein change has occoured ie what codon? Thanks
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Devon Ryan
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oatgoat •
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oatgoat •
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If this is a change in a splice site then there may not be a change in the protein sequence at all, there might simply be no protein. Or maybe there's less protein. Or maybe there's a switch in the isoform usage.
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