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Questions related assembly algorithms?

1) What is the overarching challenges in the assembly algorithms?

2) How different algorithms handle local repeats or segmentation duplicates in the genome?

3) How do DBG, OLC, string graph, greedy and hybrid algorithms perform with different sequencing read length?

assembly dbg olc ngs illumina

To be answered, do not ask general questions that you can find in literature (just google it). Read first, decide what you do not understand, ask question about specific points, then people here will be so glade to answer.

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