I have obtained vcf files for denisovan and altai neanderthal variants (found here: http://www.eva.mpg.de/denisova/index.html). I have filtered the variants in each set using hg38 .bed files and now wish to annotate these variants using preferably annovar.

What I'd like to know is which database to use when annotating. As both sets of variants are mapped against reference human alleles, is it best to use the human database as one would for annotating 1000 genomes vcf files for instance?