Which strategy to get draft genome: rawread mapping or de novo assembly?
Hi all,
I want to generate a clean consensus genome from fastq files. I also have a close reference I would like your opinion about what is the best strategy to get a draft genome: I can't determine from bibliography the best strategy: rawread mapping or de novo assembly? or both?
Is there a reference pipeline I missed?
Thanks a lot!
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curiousbiologist •
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You can give a look here
thank you Fabio! very usefull