Ok, I got it! Thanks a lot!
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konstantinkul
Interproscan GO terms results explanation
Hi all,
I am new in InterPro scan as well as in genome annotation. I need to classify genes by GO terms to obtain a general table "GO Terms Classification Count Results" Could you please explain me one thing. When I run Interproscan with '-goterms' option it generated for me such output where several GO terms appear? So I need parsing this string to get only one or I need get all of them for further analysis (for instance https://www.animalgenome.org/bioinfo/tools/catego/) ? And what exactly means if several GOs appear?
H31_00826 08305e1960d087dfd44f6179ca32d6b9 88 SMART SM01387 7 87 1.3E-47 T 21-08-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412
Thank you in advance!
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Michael Dondrup
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konstantinkul
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konstantinkul
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A given protein may be annotated with multiple terms from the same or multiple domains. In your example, the protein is annotated as being involved in translation (GO:0006412, biological process domain) and as being part of the ribosome (GO:0005840, cellular component domain). So if you want to understand your protein, you need to parse all these terms. Sometimes a protein may be annotated with both a term and one or more of its children (an ontology is a directed acyclic graph), in which case you may want to keep one or more depending on the level of specificity you need.
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Jean-Karim Heriche
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WouterDeCoster
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