Normalization of NGS data to make CNV calls
Hi Biostars Community,
I have low-coverage (~ 1X) WGS data for 5 disease and 5 controls samples. I want to make CNV calls using this data.
My question is, do I need to normalize reads for ALL the samples before making CNV calls? If so, could you please suggest an R package to do so!
Thanks a lot for the help.
Best regards, Akhil
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caspase8mach •
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