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Hub gene analyses

Hello everyone

I have RNA seq data and I would like to find hub gene in my data set. Do you have any idea which package or software I should use?

Thanks for helping

rna-seq r
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updated by Jean-Karim Heriche Jean-Karim Heriche • written by saj98 saj98

2 answers

You can identify modules and their hub genes using WGCNA

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written by WouterDeCoster WouterDeCoster

Hello Wouter

I have six samples. Can I use WGCNA to find hub gene.

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written by saj98 saj98

I have one more query, in WGCA, I need to prepare clinical trait. I do not have the clinical trait, I have RNA seq value for each sample. How I should prepare CSV file for clinical trait.

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written by saj98 saj98

By definition a hub is a high-degree node. You find them by looking at the distribution of node degrees for your graph. If working with the adjacency matrix, node degrees are easily obtained by summing over the rows/columns.

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written by Jean-Karim Heriche Jean-Karim Heriche

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