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Comparing open chromatin data to ChromHMM model

Hi, curious about the best way to go about seeing where ATAC-seq peaks fall in a ChromHMM state model of a number of histone marks and TFs? To build a model pulled GEO data for marks and TFs from papers and would like to compare to our ATAC data. Thanks.

chromhmm chip-seq atac-seq

1 answer

Is it human data ? Check different chromatin states from epigenome roadmap for various tissues. You can represent the enichments of ATAC peak in various regulatory elements.

No this is actually mouse data.

You can check chromatin states in mouse. For example, I found one quickly here from mouse ENCODE.

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